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GSK-5959 (3a) also displays selectivity over the closely related family members
Smiles: CC(=O)O/N=C1/C2=CC(Cl)=CC=C2N(CC2=CC(Cl)=CC=C2Cl)C/1=O
It is a natural product isolated from the corn lily (Veratrum californicum)
I-BET762 is currently in clinical development for oncology indication
Oral dosing of GNF7156 in diabetic mice induces β-cell proliferation
DMAT - CAS# 749234-11-5 60256 GSK-5959 (3a) also displays selectivityDMAT, CAS No. 749234 11 5, is a potent and specific CK2 inhibitor with an IC50 value of 130 nM. Product information CAS Number: 749234 11 5 Molecular Weight: 476. 79 Formula: C9H7Br4N3 Synonym: CK2 Inhibitor Casein kinase II Inhibitor Chemical Name: DMAT Smiles: CN(C)C1NC2=C(N=1)C(Br)=C(Br)C(Br)=C2Br InChiKey: SLPJGDQJLTYWCI UHFFFAOYSA N InChi: InChI=1S C9H7Br4N3 c1 16(2)9 14 7 5(12)3(10)4(11)6(13)8(7)15 9 h1 2H3,(H,14,15) Technical Data Appearance: