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Gliotoxin Suppresses Macrophage Immune Function by Subverting Phosphatidylinositol 3
It shows no inhibitory activity against the type I (PRMT1 and PRMT4) and type II (PRMT7) PRMT family members
Smiles: CC1NC(=O)C2=CC(CN(CC#C)C3=CC(F)=C(C=C3)C(=O)N[C@@H](CCC3N=NNN=3)C(O)=O)=C(C)C=C2N=1
InChiKey: JHSXDAWGLCZYSM-UHFFFAOYSA-N
Although it failed Phase II clinical trials for ADHD
Tubastatin A Size:Contact [email protected] for quotation Gliotoxin Suppresses Macrophage Immune FunctionTubastatin A is a potent and selective HDAC6 inhibitor with an IC50 of 15 nM in a cell free assay, and is selective (1000 fold more) against all other isozymes except HDAC8 (57 fold more). Product information CAS Number: 1252003 15 8 Molecular Weight: 335. 40 Formula: C20H21N3O2 Chemical Name: N hydroxy 4 ({2 methyl 1H,2H,3H,4H,5H pyrido[4,3 b]indol 5 yl}methyl)benzamide Smiles: CN1CC2=C(CC1)N(CC1=CC=C(C=C1)C(=O)NO)C1C=CC=CC2=1 InChiKey: