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Brevetoxin-3 (PbTx-3) is a potent allosteric voltage-gated Na+ channel activator and has multiple active centers (A-ring lactone
PR-104 (sodium)
COC1=CC(=CC(OC)=C1O)C1=[O+]C2C=C(O)C=C(O)C=2C=C1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
HepG2 cells and PC-9 lung cancer cell lines harboring EGFR exon 19 del with IC50s of 68 nM
rats and dogs (F=45
Firsocostat Size:Contact [email protected] for quotation Brevetoxin-3 (PbTx-3) is a potentFirsocostat (ND 630; GS 0976; NDI 010976) is an acetyl CoA carboxylase (ACC) inhibitor; inhibits human ACC1 and ACC2 with IC50 values of 2. 1 and 6. 1 nM, respectively. Product information CAS Number: 1434635 54 7 Molecular Weight: 569. 63 Formula: C28H31N3O8S Chemical Name: 2 {1 [(2R) 2 (2 methoxyphenyl) 2 (oxan 4 yloxy)ethyl] 5 methyl 6 (1,3 oxazol 2 yl) 2,4 dioxo 1H,2H,3H,4H thieno[2,3 d]pyrimidin 3 yl} 2 methylpropanoic acid Smiles:
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