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VX-809 (3 μM) treatment increases F508del-CFTR exit from the ER by 6 fold
Flavopiridol exhibits potent cytotoxicity against a wide variety of tumor cell lines with IC50 values ranging form 16 nM for LNCAP to 130 nM for K562
Smiles: CC1N=CSC=1C1C=CC(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCC(O)=O)C(C)(C)C)=CC=1
which binds covalently to the active site of thymidylate synthase
HG-10-102-01 is the first compound reported to be capable of inhibiting Ser910 and Ser935 phosphorylation in mouse brain following intraperitoneal delivery of doses as low as 50 mg/kg
Dextran sulfate sodium (DSS) 43943A VX-809 (3 μM) treatment increasesDextran sulfate sodium (DSS) is a potent and selective inhibitor of human immunodeficiency virus type 1 (HIV 1) in vitro that inhibits virus adsorption to the host cells. Product information CAS Number: 9011 18 1 Synonym: Dextran sulfate sodium salt Chemical Name: Dextran sulfate sodium (DSS) Technical Data Appearance: Solid Power Purity: 98% (or refer to the Certificate of Analysis) Solubility: Water 100 mg mL Shipping Condition: Shipped under
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