Trametinib DMSO solvate - CAS# 1187431-43-1 Catalog No.:M10955-10 HG-6-64-1 is a selective B-Raf

HG-6-64-1 is a selective B-Raf and mutant B-Raf inhibitor

InChi: InChI=1S/C23H11ClN4/c24-15-8-9-18-19(10-15)16-6-1-2-7-17(16)21-22(18)28-23(27-21)20-13(11-25)4-3-5-14(20)12-26/h1-10H

preceded by desmosterol changes that would serve as a predictive safety biomarker for lenticular opacity

Molecular Weight: 915

Vitamin B3

Trametinib DMSO solvate - CAS# 1187431-43-1 Catalog No.:M10955-10 HG-6-64-1 is a selective B-RafTrametinib, also known as GSK1120212, is a n orally bioavailable inhibitor of mitogen activated protein kinase kinase (MEK MAPK ERK kinase) with potential antineoplastic activity. Trametinib specifically binds to and inhibits MEK 1 and 2, resulting in an inhibition of growth factor mediated cell signaling and cellular proliferation in various cancers. MEK 1 and 2, dual specificity threonine tyrosine kinases often upregulated in various cancer cell