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BDTX-189 exhibits anticancer activity
the inhibition of which is linked to a potential risk of myelosuppression
InChi: InChI=1S/C15H10O4/c1-7-11(16)6-10-12(13(7)17)15(19)9-5-3-2-4-8(9)14(10)18/h2-6
together with promising early efficacy signals and a favorable safety profile
Hydroxyfasudil hydrochloride
PDE9-IN-1 nib Hydrochloride BDTX-189 exhibits anticancer activityPDE9 IN 1 is a potent, selective, and orally bioavailable phosphodiesterase 9A (PDE9A) Inhibitor with an IC50 of 8. 7 nM. Product information CAS Number: 2305087 92 5 Molecular Weight: 362. 40 Formula: C17H23FN6O2 Chemical Name: 1 cyclopentyl 6 {[(2R) 1 [(3S) 3 fluoropyrrolidin 1 yl] 1 oxopropan 2 yl]amino} 1H,4H,5H pyrazolo[3,4 d]pyrimidin 4 one Smiles: C[C@@H](NC1NC(=O)C2C=NN(C3CCCC3)C=2N=1)C(=O)N1C[C@@H](F)CC1 InChiKey: HOQGZKUBNCAZBE MNOVXSKESA N
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