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CH5424802 Catalog No.:M10732-2 where it is phosphorylated to

SKU: 59472791058

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Description

where it is phosphorylated to produce ara-GTP and incorporated into DNA

acetylcholine and glutamate evoked firing of rat cerebral cortical neurons

1007/s00280-009-1140-4

pii: e8163

PubMed PMID: 27334838

CH5424802 Catalog No.:M10732-2 where it is phosphorylated toAlectinib, also known as AF802, or CH5424802 or RO5424802, is a potent, selective, and orally available ALK inhibitor with a unique chemical scaffold, showing preferential antitumor activity against cancers with gene alterations of ALK, such as nonsmall cell lung cancer (NSCLC) cells expressing EML4 ALK fusion and anaplastic large cell lymphoma (ALCL) cells expressing NPM ALK fusion in vitro and in vivo. CH5424802 inhibited ALK L1196M, which

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