Pay in 4 interest-free payments of $8.00 Learn more
Ships within 48 hours · Estimated delivery Aug 1 - Aug 6
ADX47273 reduced rat-conditioned avoidance responding [minimal effective dose (MED) = 30 mg/kg i
How to use
and the nuclear factors of activated T cells (NFAT) family of transcription factors are defined as likely mediators of human beta cell proliferation and differentiation
The X-ray co-crystal structures revealed the daminozide’s inhibition mode: it binds in the 2OG binding pocket and chelates to the active site metal via its acylhydrazide carbonyl and dimethylamino groups
Formula: C20H23N3O3
CP-690550 - JAK Inhibitor. CAS# 477600-75-2 0216 ADX47273 reduced rat-conditioned avoidance respondingCP 690550, CAS No. 477600 75 2, is a potent and selective JAK inhibitor currently in clinical trials for rheumatoid arthritis (RA) and other autoimmune disease indications. It inhibits recombinant human JAK1 (IC50 ~ 3. 2 nM), JAK2 (IC50 ~4. 1 nM), and JAK3 (IC50 ~1. 6 nM). In cellular assays CP 690550 showed potent effects in the IL 2 blast proliferation assay (IC50 ~11 nM, mediated via JAK1 and JAK3) and HU03 cellular specificity assay (IC50 ~324 nM,
US$ 750.00
US$ 2600.00
US$ 750.00
US$ 800.00
US$ 800.00
US$ 1200.00
US$ 400.00
US$ 750.00
US$ 1000.00
US$ 800.00
US$ 800.00
US$ 400.00
US$ 720.00
US$ 1200.00
US$ 400.00
US$ 625.00
US$ 750.00
US$ 600.00
US$ 1600.00