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10 mM abolishes ABCG2 activity
AT13148 inhibits a panel of kinases at 10 μM
PubMed PMID: 21639821
second messengers
1639042-08-2
Setiptiline Catalog No.:M8150-2 10 mM abolishes ABCG2 activitySetiptiline, also known as MO 8282 and teciptiline, is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). It was launched in 1989 for the treatment of depression in Japan by Mochida. Setiptiline acts as a norepinephrine reuptake inhibitor,[3] 2 adrenergic receptor antagonist, and serotonin receptor antagonist, likely at the 5 HT2A, 5 HT2C, and or 5 HT3 subtypes, as well as an H1 receptor
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