Hexa-D-arginine TFA eic acid benzyl ester-d5 which binds RIP3 kinase domain

which binds RIP3 kinase domain with an IC50 of 8

19(1):291-300

representing an approximately 30-fold decrease in activity relative to the human T-cell/HUVEC assay data (ICIC50=2

1'-biphenyl]-4-carbonyl}pyrrolidin-3-imine

21(14):3263-73

Hexa-D-arginine TFA eic acid benzyl ester-d5 which binds RIP3 kinase domainHexa D arginine TFA (Furin Inhibitor II TFA) is a stable furin inhibitor with Ki values 106 nM, 580 nM and 13. 2 M for furin, PACE4 and prohormone convertase 1 (PC1), respectively. Hexa D arginine TFA blocks Pseudomonas exotoxin A and anthrax toxins toxicity in vitro and in vivo. Product information CAS Number: 958204 56 3 Molecular Weight: 1159. 23 Formula: C38H85F3N24O14 Chemical Name: hexakis(2 amino 5 [(diaminomethylidene)amino]pentanoic acid);