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including retraction and cell rounding and reduced actin bundles of cultured trabecular meshwork (TM) cells
19(19):5576-81
CAS Number: 31430-18-9
2016 Jul 26
InChiKey: DADYQGIQOBJGIW-HNCPQSOCSA-N
Delpazolid - CAS# 1219707-39-7 057 including retraction and cell roundingDelpazolid, CAS No. 1219707 39 7, also known as LCB01 0371, is a new oxazolidinone with cyclic amidrazone. In vitro activity of LCB01 0371 against 624 clinical isolates was evaluated and compared with those of linezolid, vancomycin, and other antibiotics. LCB01 0371 showed good activity against Gram positive pathogens. In vivo activity of LCB01 0371 against systemic infections in mice was also evaluated. LCB01 0371 was more active than linezolid