Chymostatin 4885614 C[C@@H](O)[C@H](CCCCCC)N1C=NC2=C(N)N=CN=C12

C[C@@H](O)[C@H](CCCCCC)N1C=NC2=C(N)N=CN=C12

InChiKey: YCIOJDKGCWAHLR-UHFFFAOYSA-N

InChi: InChI=1S/C25H27NO2/c1-3-24(19-7-5-4-6-8-19)25(20-9-13-22(27)14-10-20)21-11-15-23(16-12-21)28-18-17-26-2/h4-16

with 50 nM PU-H71 needed to significantly reduce the LPS dependent nitrite release

associated with decreased c-Myc

Chymostatin 4885614 C[C@@H](O)[C@H](CCCCCC)N1C=NC2=C(N)N=CN=C12Chymostatin is a bioactive peptide of microbial origin that acts as a protease inhibitor with selectivity for chymotryptase like serine proteases. It potently inhibits chymotrypsin and chymase (Ki = 9. 36 and 13. 1 nM, respectively) while less effectively blocking the activity of cathepsins, papain, and leukocyte elastase.,,,, It is without effect on trypsin, thrombin, plasmin, pepsin, and kallikrein. Product information CAS Number: 9076 44 2