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3-dimethyl-1H-pyrazole-5-carboxamide (TAK-593)
CN1CCN(CC1)C(=O)CN[C@@H]1C[C@H]1C1C=CC(=CC=1)OCC1C=CC=CC=1 |&1:13
Molecular Weight: 2180
Formula: C21H20ClFN4O5S
Target identification for a Hedgehog pathway inhibitor reveals the receptor GPR39
Malantide TFA Catalog No.:M11753-10 3-dimethyl-1H-pyrazole-5-carboxamide (TAK-593)Malantide TFA is a synthetic dodecapeptide derived from the site phosphorylated by cAMP dependent protein kinase (PKA) on the subunit of phosphorylase kinase. Malantide TFA is a highly specific substrate for PKA with a Km of 15 M and shows protein inhibitor (PKI) inhibition >90% substrate phosphorylation in various rat tissue extracts. Malantide TFA is also an efficient substrate for PKC with a Km of 16 M. Product information Molecular Weight: 1747.
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