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Continuous administration of DS-1001b impairs tumor growth in xenograft mice
It mediates cell adhesion to serum proteins and extracellular matrix via the recognition of the arg-gly-asp (RGD) sequence
which is a triazole antifungal intended for oral treatment of superficial and systemic mycoses
Inhibition of transmembrane transport may result in increased intracellular concentrations of an anticancer drug
CAS Number: 132-20-7
SR-318 Catalog No.:M28089-C Continuous administration of DS-1001b impairsSR 318 is a potent and highly selective p38 MAPK inhibitor with IC50s of 5 nM, 32 nM and 6. 11 M for p38, p38 and p38 , respectively. SR 318 potently inhibits the TNF release in whole blood with an IC50 of 283 nM. SR 318 has anti cancer and anti inflammatory activity. Product information CAS Number: 2413286 32 3 Molecular Weight: 459. 58 Formula: C27H33N5O2 Chemical Name: 5 amino N ({4 [(3 cyclohexylpropyl)carbamoyl]phenyl}methyl) 1 phenyl 1H pyrazole
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