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CCT251545 potently inhibits WNT pathway activity in COLO205-F1756 clone 4 (an APC -mutant human colorectal cancer cell line engineered to express a modified luciferase-based WNT reporter construct) with an IC50 of 0
Smad2 and Smad3
rats receiving Mibefradil or NSC 64013 show significant lower CaV3
is a potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and antitumor activities in breast cancer
Formula: C28H29NO6
VH 032 amide-alkylC6-acid - CAS# 2172819-75-7 791343 dihydrochloride CCT251545 potently inhibits WNT pathwayVH 032 amide alkylC6 acid, CAS No. 2172819 75 7, is a VHL ligand with alkyl linker and terminal acid for onward chemistry. Product information CAS Number: 2172819 75 7 Molecular Weight: 586. 74 Formula: C30H42N4O6S Synonym: VH 032 amide alkylC6 acid VH 032 amide alkylC6 VH032 amide alkylC6 acid VH032amide alkylC6 acid VH 032amide alkylC6 Chemical Name: 8 (((S) 1 ((2S,4R) 4 hydroxy 2 ((4 (4 methylthiazol 5 yl)benzyl)carbamoyl)pyrrolidin 1 yl) 3,3