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6(3):372-83
856243-80-6
InChi: InChI=1S/C19H18N4O3
InChi: InChI=1S/C18H15ClF3N3O2/c1-17(26
2% Tween-80 (MCT))
PKC-IN-1 - CAS# 1046787-18-1 size:10mg solid 6(3):372-83PKC IN 1, CAS No. 1046787 18 1, is a potent, ATP competitive and reversible inhibitor of conventional PKC enzymes with Kis of 5. 3 and 10. 4 nM for human PKC and PKC, and IC50s of 2. 3, 8. 1, 7. 6, 25. 6, 57. 5, 314, 808 nM for PKC, PKCI, PKCII, PKC, PKC, PKC mu and PKC, respectively. IC50: 2. 3 nM (Human PKC), 7. 6 nM (Human PKCII), 8. 1 nM (Human PKCI), 25. 6 nM (Human PKC), 57. 5 nM (Human PKC), 314 nM (Human PKC mu), 808 nM (Human PKC) Ki: 5. 3 nM
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