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PHT-427 Size:2mg solid InChiKey: RTIXKCRFFJGDFG-UHFFFAOYSA-N

SKU: 41646526601

4.7
USD113.05 USD146.05

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Description

InChiKey: RTIXKCRFFJGDFG-UHFFFAOYSA-N

individual plaques could be distinguished within 30 to 60 min after a single IV injection or a single IP injection of Methoxy-X04

and RPS6KA1 with IC50 values of 11

CNQX (FG9065

hydrolyzing long-chain fatty acid esters and thioesters) and promotes lipid storage in adipocytes

PHT-427 Size:2mg solid InChiKey: RTIXKCRFFJGDFG-UHFFFAOYSA-NPHT 427 is an AKT inhibitor that inhibits AKT and PDPK1 at low micromolar concentrations in numerous cancer cell lines and exhibits good oral anti tumor activity in mouse xenograft models. PHT 427 reduces the phosphorylation of AKT and PDPK1. Following the administration of a single oral dose of PHT 427 to mice bearing BxPC 3 human pancreatic tumor xenografts, PHT 427 inhibited the phosphorylation of both Akt and PDPK1 as well as downstream targets

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