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(R)-Plevitrexed 20063 Smiles: CCN1CC2=C3NC(=O)/C(=N/O)/C3=CC(C3C=CC=CC=3)=C2CC1

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Description

Smiles: CCN1CC2=C3NC(=O)/C(=N/O)/C3=CC(C3C=CC=CC=3)=C2CC1

IC50:16 nM Org 25543 hydrochloride is a potent and selective glycine transporter type 2 (GlyT2) inhibitor for hGlyT2

It can also increase the availability of dopamine by inhibiting uptake through the dopamine transporter

In the same model

Recent studies demonstrates that high levels of different isoform of CaMK

(R)-Plevitrexed 20063 Smiles: CCN1CC2=C3NC(=O)/C(=N/O)/C3=CC(C3C=CC=CC=3)=C2CC1(R) Plevitrexed ((R) ZD 9331; (R) BGC9331) is a less active enantiomer of Plevitrexed. Plevitrexed is an orally active and potent thymidylate synthase (TS) inhibitor. Product information CAS Number: 153537 74 7 Molecular Weight: 532. 53 Formula: C26H25FN8O4 Chemical Name: (2R) 2 [(4 {[(2,7 dimethyl 4 oxo 3,4 dihydroquinazolin 6 yl)methyl](prop 2 yn 1 yl)amino} 2 fluorophenyl)formamido] 4 (2H 1,2,3,4 tetrazol 5 yl)butanoic acid Smiles:

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