L-765314 Catalog No.:M20115-C CAS Number: 104561-41-3

CAS Number: 104561-41-3

The Journal of Nutrition

InChi: InChI=1S/C72H78ClF2N15O14/c1-100-60-39-56-51(66(79-43-78-56)80-45-18-20-54(75)52(73)37-45)38-61(60)104-30-9-3-4-15-62(91)81-58(42-103-41-46-40-89(86-83-46)29-32-102-34-33-101-31-24-76-55-14-10-13-49-65(55)72(99)90(71(49)98)59-21-22-63(92)82-69(59)96)68(95)77-23-8-2-5-16-64(93)87-25-27-88(28-26-87)70(97)50-35-44(17-19-53(50)74)36-57-47-11-6-7-12-48(47)67(94)85-84-57/h6-7

ONX-0914 was dosed to mice by either intravenous or subcutaneous administration at 2-10 mg/kg once a day for 5 days

In cell free biochemical assays

L-765314 Catalog No.:M20115-C CAS Number: 104561-41-3L 765314 is a potent and selective 1b adrenergic receptor antagonist with Kis of 5. 4 nM and 2. 0 nM for rat and human 1b adrenergic receptor, respectively. Product information CAS Number: 189349 50 6 Molecular Weight: 522. 60 Formula: C27H34N6O5 Chemical Name: benzyl (2S) 4 (4 amino 6,7 dimethoxyquinazolin 2 yl) 2 (tert butylcarbamoyl)piperazine 1 carboxylate Smiles: CC(C)(C)NC(=O)[C@@H]1CN(CCN1C(=O)OCC1C=CC=CC=1)C1N=C2C=C(OC)C(=CC2=C(N)N=1)OC