KPT-330 - CAS# 1393477-72-9 009 but not activity of other

but not activity of other SCF complexes

2014:149628

enzymes and transporters

CAS Number: 1418033-25-6

administration of NLG919 markedly enhanced the antitumor responses of naïve

KPT-330 - CAS# 1393477-72-9 009 but not activity of otherKPT 330, CAS No. 1393477 72 9, is an orally bioavailable, potent and selective XPO1 CRM1 Inhibitor. KPT 330 is effective in acquired resistance to ibrutinib and synergizes with ibrutinib in chronic lymphocytic leukemia. KPT 330 potentiates the antitumor activity of gemcitabine in human pancreatic cancer through inhibition of tumor growth, depletion of the antiapoptotic proteins, and induction of apoptosis. KPT 330 has strong activity against primary