A-437203 Catalog No.:M18760-C InChi: InChI=1S/C21H20O10/c1-7-2-9-14(11(23)3-7)18(27)15-10(16(9)25)4-8(5-12(15)24)30-21-20(29)19(28)17(26)13(6-22)31-21/h2-5

InChi: InChI=1S/C21H20O10/c1-7-2-9-14(11(23)3-7)18(27)15-10(16(9)25)4-8(5-12(15)24)30-21-20(29)19(28)17(26)13(6-22)31-21/h2-5

Formula: C22H17ClF3N3O7

2016 Dec 20

and demonstrates good in vivo activity in models of inflammation

used as the cytotoxic component in antibody-drug conjugates (ADC)

A-437203 Catalog No.:M18760-C InChi: InChI=1S/C21H20O10/c1-7-2-9-14(11(23)3-7)18(27)15-10(16(9)25)4-8(5-12(15)24)30-21-20(29)19(28)17(26)13(6-22)31-21/h2-5A 437203 is a selective D3 receptor antagonist with Ki of 71, 1. 6, and 6220 nM for D2, D3, and D4 receptors, respectively. Product information CAS Number: 220519 06 2 Molecular Weight: 456. 53 Formula: C20H27F3N6OS Chemical Name: 2 [(3 {4 [2 tert butyl 6 (trifluoromethyl)pyrimidin 4 yl]piperazin 1 yl}propyl)sulfanyl] 3,4 dihydropyrimidin 4 one Smiles: CC(C)(C)C1N=C(C=C(N=1)C(F)(F)F)N1CCN(CCCSC2NC(=O)C=CN=2)CC1 InChiKey: KXVAICSRMHXLJN UHFFFAOYSA N