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48 hours) abrogates DOX-induced upregulation of mesenchymal markers and the downregulation of epithelial markers in human HCC cell lines
Smiles: OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OCC1C2=CC=CC=C2C2=CC=CC=C21
InChiKey: BNAUPWAOLQXQJZ-KPOBHBOGSA-N
when administered alone
Preparation of amino acid-based hydroxamic acids as histone deacetylase (HDAC) inhibitors
(Rac)-Tavapadon 23583 48 hours) abrogates DOX-induced upregulation(Rac) Tavapadon ((Rac) PF 06649751) is a potent and selective noncatechol dopamine D1 receptor agonist. (Rac) Tavapadon displays potent full agonism in the GS activation assay as well as partial agonism in the arrestin2 recruitment assay (GS cAMP, EC50=0. 8 nM; arrestin2, EC50=68 nM). (Rac) Tavapadon has antiparkinsonian activity. Product information CAS Number: 1643462 64 9 Molecular Weight: 391. 34 Formula: C19H16F3N3O3 Chemical Name: (Rac) 1, 5