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InChiKey: UZIATSFXNVOVFE-OAHLLOKOSA-N
Potent and Selective Inhibition of Histone Deacetylase 6 (HDAC6) Does Not Require a Surface-Binding Motif
Smiles: CC(C1CCN(CC1)S(=O)(=O)CC)N1C2=CC=CC=C2C(C(=O)NCC2=C(C=C(C)NC2=O)OC)=C1C
SCR7: a NHEJ inhibitor promotes the efficiency of HDR 4–5-fold for CRISPR editing in both human and mouse cell lines
Smiles: C/C(=N\NC(=S)N1CCC1)/C1=CC=CC=N1
RVX-208 - BET Bromodomain Inhibitor. CAS# 1044870-39-4 60428 InChiKey: UZIATSFXNVOVFE-OAHLLOKOSA-NRVX 208, CAS No. 1044870 39 4, also known as Apabetalone, is a potent inhibitor of BET bromodomains. RVX 208 functions by removing atherosclerotic plaque via reverse cholesterol transport (RCT). RVX 208 increases the production of ApoA I in hepatocytes in vitro, and in vivo in monkeys and humans, which results in increased HDL C, but the molecular target was not previously reported. RVX 208 may be a promising new approach to the treatment of
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