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) results in a significant reduction in lesion size at 28 days in histological assessment
42 nM on CK2
Solubility: DMSO : ≥ 36 mg/mL (33
Oral dosing with either 10 or 30 mg/kg SC-560 1 hour before assay completely inhibits ionophore-stimulated TxB2production
Smiles: NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
Finerenone 28283 ) results in a significantFinerenone (BAY 94 8862) is a third generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist (IC50=18 nM). Finerenone displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500 fold). Finerenone has the potential for cardiorenal diseases research, such as type 2 diabetes mellitus and chronic kidney disease. Product information CAS Number: