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104(7):1116-25
CAS Number: 4727-31-5
Unlike broad-spectrum HDAC inhibitors
919973-83-4
(2001) Neurosci Lett 308: 37-40
MHY1485 - mTOR Activator. CAS# 326914-06-1 Catalog No.:M60189-10S 104(7):1116-25MHY1485, CAS No. 326914 06 1, is a novel potent, selective and cell permeable mTOR activator. It suppressed the basal autophagic flux, and this inhibitory effect was clearly confirmed in cells under starvation, a strong physiological inducer of autophagy. It can increase cellular mTOR Ser2448 and downstream substrate 4E BP Thr37 46 phosphorylation level in rat liver Ac2F cells (1 to 2 M for 1 h). It affects culture viability only at much higher
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