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is a highly potent and selective inhibitor of DOT1L methyltransferase with Ki of 70 pM
InChiKey: VQFIXEMZYHCOIK-UHFFFAOYSA-N
952(1-2): p
Chemical Name: N-((R)-1-(3-amino-5-(trifluoromethyl)phenyl)ethyl)-7-methoxy-2-methyl-6-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-4-amine
Chemical Name: 4-(4-aminobutoxy)-2-(2
4-Hydroxynonenal tyl-7-aminocephalosporanic acid is a highly potent and4 Hydroxynonenal (4 HNE) is an , unsaturated hydroxyalkenal and an oxidative nitrosative stress biomarker. 4 Hydroxynonenal is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2). 4 Hydroxynonenal can modulate a number of signaling processes mainly through forming covalent adducts with nucleophilic functional groups in proteins, nucleic acids, and membrane lipids. 4 Hydroxynonenal plays an important role in cancer through
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