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Prexasertib dimesylate - CAS# 1234015-58-7 Size:Contact [email protected] for quotation Formula: C7H16O6S

SKU: 63519839935

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Description

Formula: C7H16O6S

SR-01000075442

Smiles: COC1=CC(=CC(OC)=C1OC)[C@H]1[C@H]2[C@H](COC2=O)[C@@H](O)C2=CC3OCOC=3C=C21

21R)-21-amino-20-hydroxy-17-isobutyl-2

Tigloylgomisin P displays weak cytotoxicity against A549 cells (GI50=18

Prexasertib dimesylate - CAS# 1234015-58-7 Size:Contact [email protected] for quotation Formula: C7H16O6SPrexasertib dimesylate (LY2606368 dimesylate) is a selective, ATP competitive second generation checkpoint kinase 1 (CHK1) inhibitor with a Ki of 0. 9 nM and an IC50 of <1 nM. Prexasertib dimesylate inhibits CHK2 (IC50=8 nM) and RSK1 (IC50=9 nM). Prexasertib dimesylate causes double stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib dimesylate shows potent anti tumor activity. Product information CAS Number: 1234015

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