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The destroy clause can be especially destructive

Copying that creature so you attack all your opponents at once

If you flicker a face down instant or sorcery, the card wont enter the battlefield at all and will remain in whatever zone the flicker effect put it in (usually exile)

Monument to Endurance (L: $4, H: $15, C: $11) This is one of the top inclusions from EDHREC, not least because there are two Zombie commanders who want to discard cards, and Varina has also been newly popular

The upkeep cost of just one blue mana is trivial to pay

Dissipation Field is similar in what it does, only it ruins tempo rather than destroying creatures