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Palbociclib-propargyl 314entane-1 5-diamine dihydrochloride Fmoc-Ile-Ser(psi(Me

SKU: 70671998944

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Description

Fmoc-Ile-Ser(psi(Me

Duocarmycin DM is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity

and orally active inhibitor of p38α MAPK with a Ki of 101 nM

when the mutations occur around the chromophore binding pocket of rhodopsin

2014 Feb 8

Palbociclib-propargyl 314entane-1 5-diamine dihydrochloride Fmoc-Ile-Ser(psi(MePalbociclib propargyl is a ligand for target protein CDK6 for PROTAC, and binds to CRBN ligand via a PEG linker to make a PROTAC CP 10. CP 10 shows a DC50 of 2. 1 nM for CDK6. Product information CAS Number: 2366269 23 8 Molecular Weight: 485. 58 Formula: C27H31N7O2 Chemical Name: 6 acetyl 8 cyclopentyl 5 methyl 2 ({5 [4 (prop 2 yn 1 yl)piperazin 1 yl]pyridin 2 yl}amino) 7H,8H pyrido[2,3 d]pyrimidin 7 one Smiles:

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