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ALK5 and ALK7 (IC50≥500 nM)
5×104ϵ=9
InChiKey: JYBLCDXVHQWMSU-IKABZUPCSA-N
6)23(34)18-28(5)26(3)11-10-21(32)16-20(26)17-22(33)30(27
Smiles: COC1=CC=CC(=C1)NC1=NC=NN2C=CC(CN3C[C@@H](O)[C@H](N)CC3)=C21
GNE-8505 Size:Contact [email protected] for quotation ALK5 and ALK7 (IC50≥500 nM)GNE 8505 is an orally available inhibitor of Dual leucine zipper kinase (DLK). Product information CAS Number: 1620573 48 9 Molecular Weight: 419. 44 Formula: C21H24F3N5O Chemical Name: 5 [1 (cyclopropylmethyl) 5 [(1R,5S) 3 (oxetan 3 yl) 3 azabicyclo[3. 1. 0]hexan 6 yl] 1H pyrazol 3 yl] 3 (trifluoromethyl)pyridin 2 amine Smiles: NC1=NC=C(C=C1C(F)(F)F)C1C=C(C2[C@H]3CN(C[C@H]32)C2COC2)N(CC2CC2)N=1 InChiKey: IRPVABHDSJVBNZ RTHVDDQRSA N InChi: InChI=1S