Tussilagone 27367 with high affinity for sigma

with high affinity for sigma receptors (σ1/2 IC50=47/56 nM)

Dizocilpine maleate

7-dioxatricyclo[13

Smiles: COC1=CC=C2N=CC=C([C@@H](O)[C@@H]3C[C@@H]4CC[N@]3C[C@@H]4C=C)C2=C1

Formula: C18H20N4

Tussilagone 27367 with high affinity for sigmaTussilagone, a major active component in Tussilago farfara, has anti inflammatory effect. Tussilagone ameliorates inflammatory responses in dextran sulphate sodium induced murine colitis. Tussilagone inhibits the inflammatory response and improves survival in cecal ligation and puncture (CLP) induced septic mice. Product information CAS Number: 104012 37 5 Molecular Weight: 390. 51 Formula: C23H34O5 Chemical Name: (1S,3aR,5R,7S,7aS) 1 [(1R) 1