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4-dimethoxyphenyl)ethoxy]cyclohexyl]pyrrolidin-3-ol hydrochloride
The EC50 for Cdc42 wild type and Cdc42Q61L mutant were 2
Urolithin B suppresses the phosphorylation of JNK
and inhibits IClCa in RUICC without significantly affecting L-type Ca2+ current
Declostatin hydrochloride
Torin 2 Catalog No.:M10889-2 4-dimethoxyphenyl)ethoxy]cyclohexyl]pyrrolidin-3-ol hydrochlorideTorin 2 is a novel, second generation ATP competitive inhibitor that is potent and selective for mTOR with a superior pharmacokinetic profile to previous inhibitors ((EC50 = 0. 3 nM). It has been shown that Torin 2 displayed dramatic antiproliferative activity across a panel of cancer cell lines. Torin 2 showed a powerful cytotoxic activity, inhibiting the growth of each cell line in a dose dependent manner, with an IC in the nanomolar range. Torin 2
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