Azide-C2-SS-C2-biotin oxime Proxetil disrupts transcription and reduces transmission

disrupts transcription and reduces transmission to the mosquito vector

Chemical Name: ethyl N-(2-amino-4-{[(4-fluorophenyl)methyl]amino}phenyl)carbamate

Smiles: C[C@H](C(=O)N[C@H](CO)C1C=C(F)C=C(C=1)OC)N1CC2=CC=C(C=C2C1=O)C1=NC(NC2CCOCC2)=NC=C1Cl

It occupies the extended C-site and induces a major rearrangement of Sirt2’s active site

CAS Number: 151823-14-2

Azide-C2-SS-C2-biotin oxime Proxetil disrupts transcription and reduces transmissionAzide C2 SS C2 biotin is a cleavable ADC linker used in the synthesis of antibody drug conjugates (ADCs). Product information CAS Number: 1620523 64 9 Molecular Weight: 404. 57 Formula: C14H24N6O2S3 Chemical Name: 5 [(3aS,4S,6aR) 2 oxo hexahydro 1H thieno[3,4 d]imidazol 4 yl] N {2 [(2 azidoethyl)disulfanyl]ethyl}pentanamide Smiles: [N ]=[N+]=NCCSSCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21 InChiKey: CMWHTSPPRPEKSH GVXVVHGQSA N InChi: InChI=1S