Handmade quality · Free shipping over $75 · Explore the atelier

Flavopiridol (Alvocidib) cadesine CCG-267326

SKU: 77368514890

4.5
USD100.00 USD133.00

Pay in 4 interest-free payments of $25.00 Learn more

Shipping Estimate
USA
  • USA
  • CAN

Ships within 48 hours · Estimated delivery Jul 30 - Aug 4

Description

CCG-267326

BAY-985 is a potent and highly selective TBK1/IKKε inhibitor that inhibits the cellular phosphorylation of interferon regulatory factor 3 and displays antiproliferative efficacy in the melanoma cell line SK-MEL-2

GW-7647 (100 nM) causes a 24% reduction in AQP9 protein abundance in HepG2 cells

AG-1517 rapidly suppresses autophosphorylation of the EGF receptor at low nanomolar concentrations in fibroblasts or in human epidermoid carcinoma cells and selectively blocks EGF-mediated cellular processes including mitogenesis

Epub 2011 Mar 2

Flavopiridol (Alvocidib) cadesine CCG-267326Alvocidib is a synthetic N methylpiperidinyl chlorophenyl flavone compound. As an inhibitor of cyclin dependent kinase, alvocidib induces cell cycle arrest by preventing phosphorylation of cyclin dependent kinases (CDKs) and by down regulating cyclin D1 and D3 expression, resulting in G1 cell cycle arrest and apoptosis. This agent is also a competitive inhibitor of adenosine triphosphate activity. Check for active clinical trials or closed clinical

Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy

You may also like

recommand products