Hinokiflavone FI-402257 HCl MPS1/TTK 13(6):1457-67

13(6):1457-67

2-24 hours) reduces cyclin D1 protein levels in a time-

24)34-20/h6

InChiKey: URSQNPPONHUJDL-UHFFFAOYSA-N

Chemical Name: methyl 3-(N-(2-methoxy-4-(phenylamino)phenyl)sulfamoyl)thiophene-2-carboxylate

Hinokiflavone FI-402257 HCl MPS1/TTK 13(6):1457-67Hinokiflavone is a novel modulator of pre mRNA splicing activity in vitro and in cellulo. Hinokiflavone blocks splicing of pre mRNA substrates by inhibiting spliceosome assembly, specifically preventing B complex formation. Hinokiflavone is a SUMO protease inhibitor, inhibiting sentrin specific protease 1 (SENP1) activity. Product information CAS Number: 19202 36 9 Molecular Weight: 538. 46 Formula: C30H18O10 Chemical Name: 6 [4 (5,7 dihydroxy 4 oxo