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GLP-1R Antagonist 1 oxy-PEG2-alcohol 4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23

SKU: 80668958494

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Description

4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23

14-PGJ2 (15d-PGJ2) is a cyclopentenone prostaglandin that features an electrophilic

4-oxadiazol-5-yl]methyl}acetamide

Blockade of A2AR signaling with AZD4635 could reduce tumor burden and enhance antitumor immunity

InChi: InChI=1S/C23H32N8O7/c1-38-18-12-13(31(36)37)6-7-14(18)28-20(33)15(4-2-10-26-23(24)25)29-21(34)17-5-3-11-30(17)22(35)16-8-9-19(32)27-16/h6-7

GLP-1R Antagonist 1 oxy-PEG2-alcohol 4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23GLP 1R Antagonist 1 (compound 5d) is an orally active, CNS penetrant and non competitive antagonist of glucagon like peptide 1 receptor (GLP 1R), with an IC50 of 650 nM. Product information CAS Number: 488097 06 9 Molecular Weight: 440. 73 Formula: C16H11ClF6N4O2 Chemical Name: 7 (4 chlorophenyl) 1,3 dimethyl 5,5 bis(trifluoromethyl) 1H,2H,3H,4H,5H,8H [1,3]diazino[4,5 d]pyrimidine 2,4 dione Smiles:

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