CU-3 aflumizone InChi: InChI=1S/C30H40N4O6S/c1-2-3-4-5-19-32-30(37)33-24-10-16-29(17-11-24)41(38

InChi: InChI=1S/C30H40N4O6S/c1-2-3-4-5-19-32-30(37)33-24-10-16-29(17-11-24)41(38

Smiles: CC(C)(C)[C@H](NC(=O)CCCCCC(=O)N1CCN(CC[C@H](CSC2C=CC=CC=2)NC2=CC=C(C=C2S(=O)(=O)C(F)(F)F)S(=O)(=O)NC(=O)C2C=CC(=CC=2)N2CCN(CC2)CC2CC(C)(C)CCC=2C2C=CC(Cl)=CC=2)CC1)C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@@H](C)C1C=CC(=CC=1)C1SC=NC=1C

InChi: InChI=1S/C12H13N4O4S

Pfaffendorf M

Chemical Name: 6-(3-fluorophenyl)-N-[1-(2

CU-3 aflumizone InChi: InChI=1S/C30H40N4O6S/c1-2-3-4-5-19-32-30(37)33-24-10-16-29(17-11-24)41(38CU 3 is the racemate of (5Z,2E) CU 3. (5Z,2E) CU 3 is a potent and selective inhibitor against the isozyme of DGK with an IC50 value of 0. 6 M, competitively inhibits the affinity of DGK for ATP with a Km value of 0. 48 mM. (5Z,2E) CU 3 targets the catalytic region, but not the regulatory region of DGK. (5Z,2E) CU 3 has antitumoral and proimmunogenic effects, enhances the apoptosis of cancer cells and the activation of T cells. Product information CAS