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7) and demonstrates selectivity over other neurokinin receptors (pKi NK2 = 6
which are macrolides from STREPTOMYCES avermitilis
InChi: InChI=1S/C17H18F3N3O3/c1-21-4-6-22(7-5-21)15-12(19)8-10-14(13(15)20)23(3-2-18)9-11(16(10)24)17(25)26/h8-9H
It is used in the management of gastroesophageal reflux disease
[Epub ahead of print] PubMed PMID: 25101911
BIBX 1382 - CAS# 196612-93-8 Size:Solid 10 mg 7) and demonstrates selectivity overFalnidamol, also known as BIBX 1382, is a pyrimido pyrimidine with antitumor activity. BIBX 1382 inhibits the intracellular tyrosine kinase domain of the Epidermal Growth Factor Receptor (EGFR) thus specifically reversing the aberrant enzymatic activity from overexpressed and constitutively activated EGFR, and subsequently inhibiting cell proliferation and inducing cell differentiation. Check for active clinical trials or closed clinical trials using
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