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Smiles: CCOC(=O)C1=C(F)C=CC2C=COC=21
Smiles: O=C1CCC(C2CCN(CC3C=CC(I)=CC=3)CC2)(C2C=CC=CC=2)C(=O)N1
Staurosporine is a natural product originally isolated in 1977 from the bacterium Streptomyces staurosporeus
3'-bithiophen]-5-yl}methoxy)phenyl]methyl}[(2E)-6
It induced tumor regression in mouse xenograft tumor models driven by Bcr-Abl(WT) or the mutants and significantly improved the survival of mice bearing an allograft leukemia model with Ba/F3 cells harboring Bcr-Abl(T315I)
JTE-013 Catalog No.:M11430-10 Smiles: CCOC(=O)C1=C(F)C=CC2C=COC=21JTE 013 is a potent, selective sphingosine 1 phosphate 2 (S1P2) receptor antagonist that binds to the human and rat receptors with IC50 values of 17 and 22 nM, respectively, (IC50 values >10 M for human S1P1 and S1P3). Product information CAS Number: 383150 41 2 Molecular Weight: 408. 29 Formula: C17H19Cl2N7O Chemical Name: N (2, 6 dichloro 4 pyridinyl) 2 [1, 3 dimethyl 4 (1 methylethyl) 1H pyrazolo[3, 4 b]pyridin 6 yl] hydrazinecarboxamide Smiles:
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