![AMG 925 altirelin Chemical Name: N-[4-({[(4-tert-butylphenyl)formamido]methanethioyl}amino)phenyl]-5-(dimethylamino)pentanamide hydrochloride](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M8946_1621559401.gif?v=1629869091)
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Chemical Name: N-[4-({[(4-tert-butylphenyl)formamido]methanethioyl}amino)phenyl]-5-(dimethylamino)pentanamide hydrochloride
PF 3716556
is a bactericidal drug that inhibits bacterial DNA gyrase and topoisomerase IV
a potent antagonist of the P2X7-receptor
is a potent BMP4 agonist
AMG 925 altirelin Chemical Name: N-[4-({[(4-tert-butylphenyl)formamido]methanethioyl}amino)phenyl]-5-(dimethylamino)pentanamide hydrochlorideFLX925, also known as AMG 925, is a potent and selective type 1 inhibitor of FLT3 that retains its cellular potency against clinically relevant secondary resistance mutations in FLT3 occurring with quizartinib or sorafenib treatment (FLX925 IC50: MOLM13ITD, 15 nM; MOLM13ITD D835, 28 nM; MV4 11ITD, 16 nM; MV4 11ITD D835, 19 nM; MV4 11ITD N841, 16 nM; MV4 11ITD F691, 73 nM). Product information CAS Number: 1401033 86 0 Molecular Weight: 471. 55 Formula:
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