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Argatroban SK-3 inhibitor 1 97(4):419-431

SKU: 97091991616

4.9
USD85.00 USD117.00

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Description

97(4):419-431

Ishitsuka K

8 nM and blocked ligand-stimulated activation of a chimeric EGFR-Mer protein

24)25)29-19(31)12-4-6-32(7-5-12)20-14-9-28-30-18(14)26-11-27-20

CC1=CC(=CC2=NN=C(NC3C=CC(=CC=3)OCCN3CCCC3)N=C21)C1=CC(=CC=C1Cl)OC(=O)C1C=CC=CC=1

Argatroban SK-3 inhibitor 1 97(4):419-431Argatroban is an anticoagulant that is a direct thrombin inhibitor. Argatroban was approved in 2000 for prophylaxis or treatment of thrombosis in patients with heparin induced thrombocytopenia (HIT). Argatroban is a direct thrombin inhibitor that reversibly binds to the thrombin active site. Argatroban exerts its anticoagulant effects by inhibiting thrombin catalyzed or induced reactions, including fibrin formation; activation of coagulation factors

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