bpV(phen) Catalog No.:M13702-2 10 mM to specifically inhibit

10 mM to specifically inhibit transport of nucleosides mediated by equilibrative nucleoside transporters 1 (ENT1) and 2 (ENT2)

InChi: InChI=1S/C69H124N22O19/c1-17-35(10)52(66(109)82-42(54(71)97)22-23-50(70)94)90-60(103)44(21-19-25-77-69(74)75)83-59(102)43(20-18-24-76-68(72)73)84-63(106)46(27-32(4)5)85-56(99)38(13)79-55(98)37(12)80-61(104)45(26-31(2)3)87-64(107)47(28-33(6)7)86-57(100)39(14)81-62(105)49(30-51(95)96)88-65(108)48(29-34(8)9)89-67(110)53(40(15)92)91-58(101)36(11)78-41(16)93/h31-40

Epub 2019 Oct 30

Scoulerine ((-)-Scoulerine) inhibits mini-panel of human leukemic cells

Formula: C30H37NO4

bpV(phen) Catalog No.:M13702-2 10 mM to specifically inhibitbpV(phen), a insulin mimetic agent, is a potent protein tyrosine phosphatase (PTP) and PTEN inhibitor with IC50s of 38 nM, 343 nM and 920 nM for PTEN, PTP and PTP 1B, respectively. bpV(phen) inhibits proliferation of the protozoan parasite Leishmania in vitro. bpV(phen) strongly induces the secretion of a large number of chemokines and pro inflammatory cytokines, and it activates a Th1 type pathway (IL 12, IFN). bpV(phen) can also induce cell