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InChiKey: IMJARMFRGASVMW-WKNISULPSA-N
8(3):237-51
14(6):1466-75
InChi: InChI=1S/C28H38O11/c1-15-7-11-27-12-9-19(28(27
Chemical Name: (R)-N1-((S)-3-(1H-indol-3-yl)-1-(methylamino)-1-oxopropan-2-yl)-N4-hydroxy-2-isobutylsuccinamide
WRG-28 xy-11-oxo-lanosta-8-en-24→20 lactone InChiKey: IMJARMFRGASVMW-WKNISULPSA-NWRG 28 is a selective, extracellularly acting DDR2 allosteric inhibitor with an IC50 of 230 nM. WRG 28 uniquely inhibits receptor ligand interactions via allosteric modulation of the receptor. WRG 28 inhibits tumor invasion and migration, as well as tumor supporting roles of the stroma, and inhibits metastatic breast tumor cell colonization in the lungs by targeting DDR2. Product information CAS Number: 1913291 02 7 Molecular Weight: 410. 44 Formula:
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